Myelin repair strategies: a cellular view

Myelin Repair Foundation

The Myelin Repair Foundation is pleased to present this annual review of our progress toward achieving our goal of discovering and validating effective new treatment targets for multiple sclerosis. We were extremely pleased by the rapid progress of the team both in advancing frontiers of translational scientific research and demonstrating the power of the MRF Accelerated Research CollaborationT...

Myelin Repair Foundation

• Creating new purification and culture techniques for neural cells, • Making new antibodies to visualize protein distribution or control signaling between cells, • Constructing new interfering RNAs and breeding transgenic animals to control gene expression and protein production • Developing new models to study biological mechanisms and evaluate therapeutic effects in cell culture, animal mode...

Galectin-1 in myelin repair

Galectin-1 (Gal-1) is a member of a highly conserved family of animal lectins which binds to the common disaccharide [Galβ(1-4)-GlcNAc] on both Nand O-glycans decorating cell surface glycoconjugates. Current evidence supports a role for Gal-1 in the pathophysiology of multiple sclerosis (MS), one of the most prevalent chronic inflammatory diseases, as approximately one third of MS patients gene...

Embedded Memory Test Strategies and Repair

The demand of self-testing proportionally increases with memory size in System on Chip (SoC). SoC architecture normally occupies the majority of its area by memories. Due to increase in density of embedded memories, there is a need of self-testing mechanism in SoC design. Therefore, this research study focuses on this problem and introduces a smooth solution for self-testing.  In the proposed m...

Repair of Brachial Plexus Avulsion: clinical outcome, strategies for cellular repair and MR imaging protocols